1 gene, 1 disease no more – acknowledging the full complexity of genetics could improve and personalize medicine
A whole lot more than just one genetic mutation determines whether and how disease develops. lvcandy/DigitalVision Vectors via Getty Images ~~~~~ Genetic inheritance may sound straightforward: One gene causes one trait or a specific illness. When doctors use genetics, it’s usually to try to identify a disease-causing gene to help guide diagnosis and treatment. But for most health conditions, the genetics is far more complicated than how clinicians are currently looking at it in diagnosis, counseling and treatment. Your DNA carries millions of genetic variants you inherit from your parents or develop by chance. Some are common variants, shared by many people. Others are rare variants, found...
Chief Research and Academic Officer for the Cleveland Clinic Florida Market to be inducted into Florida Inventors Hall of Fame
Joseph Iannotti, MD, PhD, to be recognized for his innovation in shoulder repair techniques and pre-operative planning software WESTON, FL: Cleveland Clinic recently announced that Joseph P. Iannotti, MD, PhD, Chief Research and Academic Officer for the Florida market, will be inducted into the Florida Inventors Hall of Fame Class of 2025 on Friday, Oct. 31, 2025, in Tampa, FL. A Fellow of the National Academy of Inventors, Dr. Iannotti holds 89 U.S. patents. He is recognized for his groundbreaking innovations in shoulder repair techniques and pre-operative planning software. “Cleveland Clinic is made up of exceptional caregivers, and Dr. Iannotti’s induction into the Florida Inventors...
Featured Video – Can GLP-1s treat alcohol use disorder?
Unveiling the crisis in addiction treatment funding
The behavioral healthcare and addiction treatment industry in Florida is facing a critical challenge. Addiction treatment providers, who deliver essential care to individuals seeking recovery, are now confronted with a development that threatens the sustainability of their services. In August 2025, detox and residential treatment facilities throughout Florida contracted with Ambetter, Centene’s ACA Marketplace product, and Sunshine Health, Centene’s Florida Medicaid Managed Care Organization, received notice announcing a significant reduction in reimbursement rates to take effect within 30 days. The new all-inclusive per diem rate, now set at $450, is well below the amount paid by the...
The pernicious infections infiltrating Ukraine’s front line
Reporting for this story was supported by the Pulitzer Center. Doctors and scientists are waging a shadow war in the besieged nation: bacteria that are resistant to multiple antibiotics. The deadly bugs are now knocking on western Europe’s door. As Hailie Uren rushed to meet the injured British soldier evacuated to her hospital in western Ukraine, the Australian clinician reflected on how vulnerable the young man must feel, speaking no Ukrainian. When she got to his bedside, he blurted out, “Oh my God, thank God!” Then he quickly asked her: “Am I going to lose my leg?” A few weeks later, on a sunny June afternoon in Lviv, the 24-year-old soldier with black curly hair and beard and intense...
